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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKAA1 All Species: 24.24
Human Site: S397 Identified Species: 44.44
UniProt: Q13131 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13131 NP_006242.5 559 64009 S397 D E L N P Q K S K H Q G V R K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086285 574 65620 S412 D E L N P Q K S K H Q G V R K
Dog Lupus familis XP_536491 563 64691 S401 D E L N P Q K S K H Q G V R K
Cat Felis silvestris
Mouse Mus musculus Q5EG47 559 63911 S397 D E L N P Q K S K H Q G V R K
Rat Rattus norvegicus P54645 559 63955 S397 D E L N P Q K S K H Q G V R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506315 519 59478 W367 Q G V R R A K W H L G I R S Q
Chicken Gallus gallus Q9IA88 798 88848 P415 D M N N P L Q P V F F P V D P
Frog Xenopus laevis NP_001083882 560 64031 T397 D E L N P Q K T K H Q V G V R
Zebra Danio Brachydanio rerio NP_001103756 573 65002 N387 R H T L D E L N P Q K S K H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623371 515 58559 S366 F S P N D T N S S P L R P H P
Nematode Worm Caenorhab. elegans Q95ZQ4 626 70425 R459 T E A S G A N R N K R A K W H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38997 535 61163 S384 P R M H P A E S V A S P V S H
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 Q428 S K S H Q K S Q V D H E T A K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.2 92.5 N.A. 98.7 99.1 N.A. 89.2 27 88.7 84.4 N.A. N.A. 62.2 53.5 N.A.
Protein Similarity: 100 N.A. 97.3 93.7 N.A. 99.4 99.6 N.A. 91 43.1 94.6 90.9 N.A. N.A. 75.1 66.4 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 6.6 26.6 66.6 0 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 20 33.3 80 20 N.A. N.A. 13.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 45 33.4 N.A.
Protein Similarity: N.A. N.A. N.A. 62.4 51.9 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 24 0 0 0 8 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 54 0 0 0 16 0 0 0 0 8 0 0 0 8 0 % D
% Glu: 0 54 0 0 0 8 8 0 0 0 0 8 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % F
% Gly: 0 8 0 0 8 0 0 0 0 0 8 39 8 0 0 % G
% His: 0 8 0 16 0 0 0 0 8 47 8 0 0 16 16 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 8 0 0 0 8 54 0 47 8 8 0 16 0 47 % K
% Leu: 0 0 47 8 0 8 8 0 0 8 8 0 0 0 8 % L
% Met: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 62 0 0 16 8 8 0 0 0 0 0 0 % N
% Pro: 8 0 8 0 62 0 0 8 8 8 0 16 8 0 16 % P
% Gln: 8 0 0 0 8 47 8 8 0 8 47 0 0 0 8 % Q
% Arg: 8 8 0 8 8 0 0 8 0 0 8 8 8 39 8 % R
% Ser: 8 8 8 8 0 0 8 54 8 0 8 8 0 16 0 % S
% Thr: 8 0 8 0 0 8 0 8 0 0 0 0 8 0 0 % T
% Val: 0 0 8 0 0 0 0 0 24 0 0 8 54 8 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _